Mastelli Plinest – Innovative Polynucleotide (PN) Formula for Multi Directional Skin Revitalization
Mastelli Plinest is an innovative biostimulating treatment developed by the Italian manufacturer Mastelli, based on polynucleotides (PN) in a gel formulation with a concentration of 40 mg/2 ml. Polynucleotides belong to a group of biologically active polysaccharides derived from salmon trout DNA. Their structure closely resembles human DNA, ensuring excellent biocompatibility and a low risk of adverse reactions.
Plinest works through multiple mechanisms: it stimulates collagen and elastin synthesis, improves skin density, provides intense hydration by binding water within deeper skin layers, and offers antioxidant protection by neutralizing free radicals and helping defend the skin against UV induced damage. The gel consistency allows for even distribution throughout the tissue after application.
Benefits
- Polynucleotides (PN) stimulate collagen and elastin biosynthesis for natural skin densification
- Intensive hydration through water retention in deeper dermal layers
- Antioxidant action that neutralizes free radicals and supports UV protection
- Improves skin texture, elasticity, and firmness
- Gel formulation ensures even product distribution after application
- Suitable for a wide range of treatment areas including face, neck, décolleté, hands, and body
Specifications
| Active Ingredient | Polynucleotides (PN) in gel form |
| Concentration | 40 mg / 2 ml |
| Volume | 2 ml |
| Packaging | 1 prefilled syringe + 2 needles |
| Needle Size | 30G × 13 mm |
| Injection Depth | Dermis (intradermal application) |
| Application Techniques | Linear, point by point, cross hatch, fan technique, or combination methods; iontophoresis and electroporation |
| Manufacturer | Mastelli, Italy |
Indications – Treatment Areas
- Skin hydration and smoothing
- Improvement of firmness and skin tension
- Anti wrinkle treatment
- Anti aging prevention
- Protection against UV radiation and free radicals
- Skin densification and stimulation of collagen and elastin synthesis
Areas: Face, neck, décolleté, hands, abdomen, buttocks, and thighs.
Who Is It For?
This product is intended exclusively for certified aesthetic medicine professionals. Intradermal application must be performed only by trained medical personnel.
Storage
Store at 2–25°C. Protect from light. Do not freeze. Use immediately after opening.
FAQ – Frequently Asked Questions
Q: What is Mastelli Plinest?
A: Mastelli Plinest is a polynucleotide based biostimulator designed to improve skin quality, hydration, elasticity, and density while supporting collagen and elastin production.
Q: How do polynucleotides work?
A: Polynucleotides stimulate fibroblast activity, support tissue regeneration, improve hydration, and provide antioxidant protection by helping neutralize free radicals.
Q: Which areas can be treated with Plinest?
A: Plinest can be used on the face, neck, décolleté, hands, abdomen, buttocks, and thighs, depending on the treatment plan established by the practitioner.
Q: What application techniques can be used?
A: The product may be administered using linear, point by point, cross hatch, fan, or combined techniques. It may also be used in conjunction with iontophoresis or electroporation protocols.
Q: How should Mastelli Plinest be stored?
A: Store between 2–25°C, away from direct light. Do not freeze. Once opened, the product should be used immediately.
Q: Why may the packaging look different?
A: The product is available in two packaging designs. Random packaging variations do not affect the quality, composition, or effectiveness of the product.
Cheeks & Mid Face, Forehead & Glabella, Lips & Perioral Area, Jawline & Chin, Neck, Décolletage, Lower Face & Marionette Lines
